E-mail: eugene.chan@cuhk.edu.hk
ORCID: 0000-0002-1463-6005
Administrative support: Ms Connie Poon
Telephone (office): (852) 3505-2839
Dr. CHAN Yu Hin, Eugene
陳宇軒醫生
Associate Professor (Clinical), Department of Paediatrics
MBBS (HK), MD (HKU), DCH (HK), DCH (International), FHKCPaed, FHKAM (Paed), FRCPCH (UK)
Research Team: Nephrology
Biography
Dr. Eugene Chan is currently a Clinical Associate Professor at the Department of Paediatrics of the Chinese University of Hong Kong. He works in the Paediatric Nephrology Centre of Hong Kong Children’s Hospital, which is the designated, territory-wide referral centre in Hong Kong.
His research interests include nephrotic syndrome, lupus nephritis, kidney failure and onconephrology. Over the past few years, he has established an international collaborative research network on nephrotic syndrome involving over 30 paediatric nephrology centres in Asia, Europe, North America and Oceania. His work has been published in top peer-reviewed nephrology journals including Kidney International and the Journal of the American Society of Nephrology.
He serves as a Co-Chair (Webinar) in the Professional Education Committee of the International Pediatric Nephrology Association and has contributed significantly to medical education in advancing global kidney care for children. He also works as an Associate Editor in Kidney International and a Section Editor in Pediatric Nephrology. Locally, he is a Council Member of the Hong Kong Paediatric Nephrology Society.
In recognition of his research and clinical contribution to the field of paediatric nephrology, he has received several international and local honours including the Young Nephrologist Award from the International Society of Nephrology, Young Investigator Award from the Asian Pacific Society of Nephrology, Young Achiever Award from the Hospital Authority, as well as Distinguished Young Fellow and Gold Medal for Best Original Research from the Hong Kong Academy of Medicine.
Research Interests
Paediatric Nephrology
Childhood nephrotic syndrome
Lupus nephritis and other paediatric glomerular disease
Kidney failure and dialysis
Onconephrology
Honorary Appointments
Honorary Associate Consultant, Paediatric Nephrology Centre, Hong Kong Children’s Hospital
Professional Service
Editorship
Associate Editor, Kidney International
Section Editor, Pediatric Nephrology
Editorial Board Member, Frontiers in Pediatrics (Pediatric Nephrology)
Editorial Board Member, Frontiers in Nephrology (Nephrology)
Others
Co-chair (webinar), Professional Education Committee, International Pediatric Nephrology Association
Junior Council, Asian Pediatric Nephrology Association
Board Member, International Pediatric Continuous Renal Replacement Therapy (pCRRT)
Council member, Hong Kong Paediatric Nephrology Society
Awards and Honours
Young Investigator Award, Asia Pacific Society of Nephrology, 2024
Distinguished Young Fellow, Hong Kong Academy of Medicine, 2023
Awardee for International Society of Nephrology, Kidney International Fellowship, 2023
Fellow, International Society of Nephrology (FISN), 2023
Silver Medal, Best Original Research, Hong Kong Academy of Medicine, 2022
Best Paediatric Research of the Year, UK Kidney Week, 2022
Young Achiever Award, Hospital Authority, 2022
Young Outstanding Staff, Hong Kong Children’s Hospital, 2022
Gold Medal, Best Original Research, Hong Kong Academy of Medicine, 2020
Young Nephrologist Award, International Society of Nephrology, 2019
Outstanding Staff and Team Award, Hospital Authority, 2017
Eugenia Lee Education Scholarship, Hong Kong Kidney Foundation, 2013
Selected Publications
Chan EYh, Yap DY, Tullus K et al. An international, multi-center study evaluated rituximab therapy in childhood steroid-resistant nephrotic syndrome. Kidney Int. 2024 Oct 10:S0085-2538(24)00700-2. doi: 10.1016/j.kint.2024.09.011. Epub ahead of print. [IF=14.8]
Chan EY, Yap HK, Tullus K et al. Long-Term Efficacy and Safety of Repeated Rituximab to Maintain Remission in Idiopathic Childhood Nephrotic Syndrome: An International Study. J Am Soc Nephrol. 2022 Jun;33(6):1193-1207. doi: 10.1681/ASN.2021111472. [IF=14.9]
Chan EY, Webb H, Tullus K et al. Both the rituximab dose and maintenance immunosuppression in steroid-dependent/frequently-relapsing nephrotic syndrome have important effects on outcomes. Kidney Int. 2020 Feb;97(2):393-401. doi: 10.1016/j.kint.2019.09.033. [IF=19.6]
Chan EY, Boyer O. Levamisole in childhood idiopathic nephrotic syndrome: new promises, and advocacy for global access. Kidney Int. 2024 May;105(5):932-934. doi: 10.1016/j.kint.2024.01.030. [IF=19.6]
Chan EY, Yap DY, Ma AL et al. Renal relapse in children and adolescents with childhood-onset lupus nephritis: a 20-year study. Rheumatology (Oxford). 2023 Aug 26:kead447. doi: 10.1093/rheumatology/kead447 [IF=7.04]
Chan EY, Parekh R, Tullus K et al. The use of rituximab in childhood idiopathic nephrotic syndrome. Clin J Am Soc Nephrol. 2023 Apr 1;18(4):533-548. doi: 10.2215/CJN.08570722. [IF=10.7]
Chan EY, Leung D, Lau YL et al. Humoral and Cellular Immunogenicity and Safety of 3-Dose Inactivated COVID-19 Vaccine in Young Children Less Than 5 Years With Kidney Diseases. Kidney Int Rep. 2023 Aug 19;8(10):2177-2179. doi: 10.1016/j.ekir.2023.08.012. [IF=5.7]
Chan EY, Yap DYH, Ma AL et al. Long-term outcomes of children and adolescents with biopsy-proven childhood-onset lupus nephritis. Kidney International Reports, 2022. Kidney Int Rep. 2022 Oct 21;8(1):141-150. DOI: https://doi.org/10.1016/j.ekir.2022. [IF=5.7]
Chan EY, Ma AL, Yap DY et al. Long-term outcomes with rituximab as add-on therapy in severe childhood-onset lupus nephritis. Pediatr Nephrol. 2023 Jun 26. doi: 10.1007/s00467-023-06025-6. [IF=3.6]
Malakasioti G, Chan EY, Tullus K et al. A multicenter retrospective study of calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene variants. Kidney Int. 2023 May;103(5):962-972. doi: 10.1016/j.kint.2023.02.022. [IF=19.6] (25 of 39 authors)
Ma AL, Leung D, Chan EY et al. Antibody responses to 2 doses of mRNA COVID-19 vaccine in pediatric patients with kidney diseases. Kidney Int. 2022 May;101(5):1069-1072. (Impact factor 18.998) doi: 10.1016/j.kint.2022.01.035. [IF=19.6] (3 of 14 authors)
Marlais M, Chan EY, Tullus K et al. Clinical Factors and Adverse Kidney Outcomes in Children With ANCA-Associated Glomerulonephritis. Am J Kidney Dis. 2022 Jul 7:S0272-6386(22)00772-7. [IF=13.2] (15 out of 60 authors)
Borzych-Dużałka D, Chan EYH, Schaefer F, Warady BA et al. Best Practice of Peritoneal Dialysis-Associated Gram-Negative Peritonitis in Children: Insights from the International Pediatric Peritoneal Dialysis Network Registry. Kidney Int Rep. 2024 Mar 28;9(6):1654-1663. doi: 10.1016/j.ekir.2024.03.031. [IF=5.7]
Chan EY, Borzych-Duzalka D, Warady et al. Colostomy in children on chronic peritoneal dialysis (A work from the International Pediatric Peritoneal Dialysis Network). Pediatr Nephrol. 2020 Jan;35(1):119-126. doi: 10.1007/s00467-019-04372-x. [IF=3.7]
Book Chapters
Chan EYH, Boyer O, K Tullus. Pediatric Glomerular Disease. Nephrology Self-assessment tool (NephSAP) 2024, an official educational material published by the American Society of Nephrology.
Chan EYH, Ma ATL, Lai WM. Development of Paediatric Nephrology in Hong Kong for “Progress in Pediatrics in Guangdong”, 2023 edition.
Ma ATL, Chan EYH, Lai WM. End stage kidney disease in children. Integrated systemic nephrology, 4thedition. The University of Hong Kong
Chan EYH, Warady BA. Acquired cystic kidney disease. Pediatric Dialysis Case Studies – A practical guide to patient care. Springer, 2017. ISBN 978-3-319-55147-0